I decided to type this up before the University of Colordo / Chromadex study is out at the end of this year or early next year when we will learn more about what the vitamin B3 supplement NR can do for us humans at 500 mg and 1000 mg, while the Elysium study showed effects of 250 mg and 500 mg although included pterostilbine as well.
I started to take 125 mg of NR last November at the age of 48 and soon noticed a change with sleep. Within a day or two, I felt my sleep was deeper and had vivid dreams as I had more often when younger. When I woke up, I was wide awake as well. Overall, I liked the changes, but it took a while to get used to.
From January, I began taking 250 mg of NR a day in the morning.
After six months, I got a haircut in April and when I rubbed my hand through my hair I could tell something was different: my hair was much thicker everywhere – in the back, on the sides and on top. I didn’t expect hair growth at all. I asked a 60 year old friend if he could tell that my hair was thicker, and he laughed: “It’s obvious!” His mostly gray/white hair had developed black streaks that became more pronounced after he took 250 mg of NR after six months and more so today at his one year mark. (He also thinks his nearsightdness has improved to when he was 40, but he hasn’t formally tested this yet with an optometrist.)
The Elysium study just published showed an almost 8% increase in the average distance walked in 6 minutes for healthy 60 to 80 year olds at 500 mg a day for 8 weeks but no increase at 250 mg. Likewise, there was a 7 to 8% average increase with a chair balance test at 500 mg but no impovement at 250 mg.
I expect to read about positive results with just 250 mg of NR a day but can also see that this might be marketed as a 375 mg and 500 mg supplement as well. Keep in mind that an obese person may find increased endurance at 250 mg as well since there metobolism is probably further from normal compared with non-obese people.
Bring on the U of Colorado results where cognitive function was measured as well!